Knockdown of TBRG4 suppresses proliferation, invasion and promotes apoptosis of osteosarcoma cells by downregulating TGF-β1 expression and PI3K/AKT signaling pathway. [electronic resource]
Producer: 20200727Description: 108351 p. digitalISSN:- 1096-0384
- Animals
- Apoptosis -- genetics
- Bone Neoplasms -- genetics
- Carcinogenesis -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- genetics
- Down-Regulation -- genetics
- Female
- Gene Knockdown Techniques
- Humans
- Lentivirus
- Mice, Nude
- Mitochondrial Proteins -- genetics
- Neoplasm Invasiveness
- Osteosarcoma -- genetics
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA, Small Interfering -- metabolism
- RNA-Binding Proteins -- genetics
- Transfection
- Transforming Growth Factor beta1 -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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