CSF1R inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice. [electronic resource]
Producer: 20210113Description: 2101-2122 p. digitalISSN:- 1945-4589
- Adipose Tissue -- drug effects
- Aging -- metabolism
- Animals
- Body Composition -- drug effects
- Body Weight -- drug effects
- Brain-Derived Neurotrophic Factor -- drug effects
- Corticotropin-Releasing Hormone -- drug effects
- Female
- Glial Fibrillary Acidic Protein -- drug effects
- Glucose Tolerance Test
- Gonadotropin-Releasing Hormone -- drug effects
- Housing, Animal
- Hypothalamus -- drug effects
- Inflammation -- genetics
- Macrophages -- drug effects
- Mice
- Microglia -- drug effects
- Neuropeptide Y -- drug effects
- Organic Chemicals -- pharmacology
- Pro-Opiomelanocortin -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor -- antagonists & inhibitors
- Social Environment
- Transcriptome -- drug effects
- Weight Loss
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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