Discovery of novel 9-heterocyclyl substituted 9H-purines as L858R/T790M/C797S mutant EGFR tyrosine kinase inhibitors. [electronic resource]
Producer: 20200218Description: 111888 p. digitalISSN:- 1768-3254
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Discovery
- Drug Screening Assays, Antitumor
- ErbB Receptors -- antagonists & inhibitors
- Heterocyclic Compounds -- chemical synthesis
- Humans
- Molecular Structure
- Mutation
- Protein Kinase Inhibitors -- chemical synthesis
- Purines -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article
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