Ebselen rescues oxidative-stress-suppressed osteogenic differentiation of bone-marrow-derived mesenchymal stem cells via an antioxidant effect and the PI3K/Akt pathway. [electronic resource]
Producer: 20200218Description: 64-70 p. digitalISSN:- 1878-3252
- Animals
- Antioxidants -- chemistry
- Azoles -- chemistry
- Cell Differentiation -- drug effects
- Cell Proliferation -- drug effects
- Cells, Cultured
- Dose-Response Relationship, Drug
- Hydrogen Peroxide -- antagonists & inhibitors
- Isoindoles
- Male
- Mesenchymal Stem Cells -- cytology
- Organoselenium Compounds -- chemistry
- Osteogenesis -- drug effects
- Oxidative Stress -- drug effects
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Rats
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Structure-Activity Relationship
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Publication Type: Journal Article
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