S1P induces pulmonary artery smooth muscle cell proliferation by activating calcineurin/NFAT/OPN signaling pathway. [electronic resource]
Producer: 20200709Description: 921-927 p. digitalISSN:- 1090-2104
- Animals
- Calcineurin -- genetics
- Calcium -- metabolism
- Cations, Divalent
- Cell Proliferation -- drug effects
- Cyclosporine -- pharmacology
- Estrenes -- pharmacology
- Female
- Gene Expression Regulation
- Ion Transport
- Lysophospholipids -- pharmacology
- Myocytes, Smooth Muscle -- cytology
- NFATC Transcription Factors -- antagonists & inhibitors
- Osteopontin -- genetics
- PPAR gamma -- antagonists & inhibitors
- Pioglitazone -- pharmacology
- Primary Cell Culture
- Pulmonary Artery -- cytology
- Pyrrolidinones -- pharmacology
- RNA, Small Interfering -- genetics
- Rats
- Rats, Sprague-Dawley
- Signal Transduction -- drug effects
- Sphingosine -- analogs & derivatives
- Type C Phospholipases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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