Therapeutic effects of artesunate on lupus-prone MRL/lpr mice are dependent on T follicular helper cell differentiation and activation of JAK2-STAT3 signaling pathway. [electronic resource]
Producer: 20200324Description: 152965 p. digitalISSN:- 1618-095X
- Animals
- Antimalarials -- pharmacology
- Artesunate -- pharmacology
- Autoantibodies -- drug effects
- Cell Differentiation -- drug effects
- Cytokines -- metabolism
- Disease Models, Animal
- Female
- Humans
- Janus Kinase 2 -- metabolism
- Lupus Erythematosus, Systemic -- drug therapy
- Lupus Nephritis -- drug therapy
- Lymphocyte Activation -- drug effects
- Male
- Mice
- Mice, Inbred MRL lpr
- STAT3 Transcription Factor -- metabolism
- Signal Transduction -- drug effects
- T-Lymphocytes, Helper-Inducer -- immunology
- T-Lymphocytes, Regulatory -- immunology
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Publication Type: Journal Article
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