Obesity-associated inflammation triggers an autophagy-lysosomal response in adipocytes and causes degradation of perilipin 1. [electronic resource]
Producer: 20200212Description: 121 p. digitalISSN:- 2041-4889
- 3T3-L1 Cells
- Adipocytes -- cytology
- Animals
- Autophagy -- drug effects
- Cathepsin B -- antagonists & inhibitors
- Culture Media, Conditioned -- pharmacology
- Humans
- Inflammation -- etiology
- Lysosomes -- metabolism
- Macrophages -- cytology
- Male
- Mice
- Mice, Inbred C57BL
- Obesity -- complications
- Palmitates -- pharmacology
- Perilipin-1 -- genetics
- Sequestosome-1 Protein -- genetics
- Tumor Necrosis Factor-alpha -- pharmacology
- Ubiquitination -- drug effects
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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