Shape-based virtual screen for the discovery of novel CDK8 inhibitor chemotypes. [electronic resource]
Producer: 20200305Description: 549-555 p. digitalISSN:- 1464-3405
- Cell Proliferation -- drug effects
- Colorectal Neoplasms -- pathology
- Cyclin-Dependent Kinase 8 -- antagonists & inhibitors
- Drug Discovery
- Drug Screening Assays, Antitumor
- G1 Phase -- drug effects
- HCT116 Cells
- Humans
- Molecular Docking Simulation
- Phosphorylation
- Protein Kinase Inhibitors -- chemistry
- S Phase -- drug effects
- STAT1 Transcription Factor -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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