Chemoprevention in BRCA1 mutation carriers (CIBRAC): protocol for an open allocation crossover feasibility trial assessing mechanisms of chemoprevention with goserelin and anastrozole versus tamoxifen and acceptability of treatment. [electronic resource]
Producer: 20191029Description: e023115 p. digitalISSN:- 2044-6055
- Adult
- Anastrozole -- therapeutic use
- Antineoplastic Agents, Hormonal -- therapeutic use
- Breast Neoplasms -- drug therapy
- Chemoprevention -- methods
- Cross-Over Studies
- Disease-Free Survival
- Feasibility Studies
- Female
- Genetic Predisposition to Disease -- epidemiology
- Goserelin -- therapeutic use
- Heterozygote
- Humans
- Mutation
- Northern Ireland
- Patient Acceptance of Health Care -- statistics & numerical data
- Patient Selection
- Premenopause -- physiology
- Prognosis
- Risk Assessment
- Survival Rate
- Tamoxifen -- therapeutic use
- Treatment Outcome
- Ubiquitin-Protein Ligases -- genetics
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Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
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