Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways. [electronic resource]
Producer: 20190822Description: 1070-1081 p. digitalISSN:- 1362-4962
- Animals
- Blood Proteins -- metabolism
- Female
- HeLa Cells
- Hepatocytes -- metabolism
- Humans
- Hydrophobic and Hydrophilic Interactions
- Kidney -- metabolism
- Lipids -- chemistry
- Lipoproteins, LDL -- metabolism
- Mice
- RNA Interference
- RNA, Small Interfering -- chemical synthesis
- Receptors, LDL -- metabolism
- Tissue Distribution
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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