Alogliptin improves endothelial function by promoting autophagy in perivascular adipose tissue of obese mice through a GLP-1-dependent mechanism. [electronic resource]
Producer: 20190731Description: 55-63 p. digitalISSN:- 1879-3649
- Adipokines -- metabolism
- Adipose Tissue -- drug effects
- Animals
- Aorta, Thoracic -- drug effects
- Autophagy -- drug effects
- Dipeptidyl-Peptidase IV Inhibitors -- pharmacology
- Disease Models, Animal
- Endothelium, Vascular -- drug effects
- Glucagon-Like Peptide 1 -- metabolism
- Male
- Mice, Inbred C57BL
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase Type III -- metabolism
- Obesity -- drug therapy
- Paracrine Communication -- drug effects
- Piperidines -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction -- drug effects
- Uracil -- analogs & derivatives
- Vasodilation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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