Regulation of human glioma cell migration, tumor growth, and stemness gene expression using a Lck targeted inhibitor. [electronic resource]
Producer: 20190514Description: 1734-1750 p. digitalISSN:- 1476-5594
- Animals
- Brain Neoplasms -- drug therapy
- Cell Movement -- drug effects
- Cells, Cultured
- Coculture Techniques
- Ganglia, Spinal -- cytology
- Gene Expression Regulation, Neoplastic -- drug effects
- Glioma -- drug therapy
- Humans
- Lymphocyte Specific Protein Tyrosine Kinase p56(lck) -- genetics
- Male
- Mice
- Neoplastic Stem Cells -- drug effects
- Oligodendroglia -- cytology
- Paxillin -- genetics
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-crk -- genetics
- Pseudopodia -- genetics
- Pyrazoles -- administration & dosage
- Pyrimidines -- administration & dosage
- Xenograft Model Antitumor Assays
- rac1 GTP-Binding Protein -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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