Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT [electronic resource]
Producer: 20191014Description: 288-305 p. digitalISSN:- 1520-4804
- Allosteric Regulation
- Allosteric Site
- Amides -- chemical synthesis
- Animals
- Azepines -- chemistry
- CHO Cells
- Calcium -- metabolism
- Cricetinae
- Cricetulus
- Drug Design
- Half-Life
- Indoles -- chemistry
- Locomotion -- drug effects
- Molecular Docking Simulation
- Piperidines -- chemistry
- Protein Isoforms -- chemistry
- Protein Structure, Tertiary
- Rats
- Receptor, Serotonin, 5-HT2C -- chemistry
- Serotonin 5-HT2 Receptor Agonists -- chemistry
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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