STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells. [electronic resource]
Producer: 20190715Description: 1057-1073 p. digitalISSN:- 1558-8238
- Active Transport, Cell Nucleus
- Animals
- Cell Line, Tumor
- Female
- HEK293 Cells
- Humans
- Immune System
- Indoleamine-Pyrrole 2,3,-Dioxygenase -- metabolism
- Interferon-beta -- pharmacology
- Kynurenine -- metabolism
- MCF-7 Cells
- Melanoma, Experimental -- metabolism
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Inbred NOD
- Mice, SCID
- Neoplastic Stem Cells -- cytology
- Phosphorylation
- Reactive Oxygen Species -- metabolism
- Receptors, Aryl Hydrocarbon -- metabolism
- STAT3 Transcription Factor -- metabolism
- Serine -- chemistry
- Signal Transduction
- Tumor Suppressor Protein p53 -- metabolism
- Tyrosine -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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