Inhibition of RPTOR overcomes resistance to EGFR inhibition in triple-negative breast cancer cells. [electronic resource]
Producer: 20180831Description: 828-840 p. digitalISSN:- 1791-2423
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Down-Regulation
- Drug Resistance, Neoplasm -- drug effects
- Drug Screening Assays, Antitumor
- Drug Synergism
- ErbB Receptors -- antagonists & inhibitors
- Female
- Gefitinib
- Gene Knockdown Techniques
- Heterocyclic Compounds, 3-Ring -- pharmacology
- Humans
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Quinazolines -- pharmacology
- RNA, Small Interfering -- metabolism
- Regulatory-Associated Protein of mTOR -- genetics
- Ribosomal Protein S6 -- metabolism
- Signal Transduction -- drug effects
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
- Triple Negative Breast Neoplasms -- drug therapy
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Publication Type: Journal Article
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