Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14α-Demethylase. [electronic resource]
Producer: 20190514ISSN:- 1098-6596
- Antifungal Agents -- chemistry
- Aspergillus fumigatus -- enzymology
- Candida albicans -- enzymology
- Catalytic Domain
- Cloning, Molecular
- Crystallography, X-Ray
- Drug Resistance, Fungal -- genetics
- Fluconazole -- chemistry
- Fungal Proteins -- chemistry
- Gene Expression
- Genetic Vectors -- chemistry
- Histidine -- genetics
- Itraconazole -- chemistry
- Kinetics
- Microbial Sensitivity Tests
- Models, Molecular
- Mutation
- Oligopeptides -- genetics
- Protein Binding
- Protein Conformation, alpha-Helical
- Protein Interaction Domains and Motifs
- Recombinant Fusion Proteins -- chemistry
- Recombinant Proteins -- chemistry
- Saccharomyces cerevisiae -- drug effects
- Sterol 14-Demethylase -- chemistry
- Substrate Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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