Traditional herbal medicine-derived sulforaphene promotes mitophagic cell death in lymphoma cells through CRM1-mediated p62/SQSTM1 accumulation and AMPK activation. [electronic resource]
Producer: 20180129Description: 11-23 p. digitalISSN:- 1872-7786
- AMP-Activated Protein Kinases -- metabolism
- Animals
- Apoptosis -- drug effects
- Cell Cycle Checkpoints -- drug effects
- Cell Proliferation -- drug effects
- Cells, Cultured
- Drugs, Chinese Herbal -- chemistry
- Humans
- Isothiocyanates -- chemistry
- Karyopherins -- metabolism
- Leukocytes, Mononuclear -- cytology
- Lymphoma -- drug therapy
- Mice
- Mice, Inbred BALB C
- Mitophagy -- drug effects
- Neoplasms -- drug therapy
- Protein Structure, Tertiary
- Raphanus -- chemistry
- Receptors, Cytoplasmic and Nuclear -- metabolism
- Sequestosome-1 Protein -- metabolism
- Signal Transduction -- drug effects
- Up-Regulation -- drug effects
- Exportin 1 Protein
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Publication Type: Journal Article
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