A mechanistic model to predict effects of cathepsin B and cystatin C on β-amyloid aggregation and degradation. [electronic resource]
Producer: 20181114Description: 21071-21082 p. digitalISSN:- 1083-351X
- Algorithms
- Amino Acid Substitution
- Amyloid beta-Peptides -- chemistry
- Cathepsin B -- chemistry
- Cystatin C -- chemistry
- Fluorescence Resonance Energy Transfer
- Humans
- Kinetics
- Models, Molecular
- Mutagenesis, Site-Directed
- Mutation
- Nerve Tissue Proteins -- chemistry
- Osmolar Concentration
- Peptide Fragments -- chemistry
- Protein Aggregation, Pathological -- metabolism
- Protein Interaction Domains and Motifs
- Proteolysis
- Recombinant Proteins -- chemistry
- Reproducibility of Results
- Solubility
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Validation Study
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