Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation. [electronic resource]
Producer: 20171030Description: e2002623 p. digitalISSN:- 1545-7885
- Alternative Splicing -- genetics
- Base Sequence
- Cell Line, Tumor
- Eukaryotic Initiation Factor-2B -- genetics
- Gene Expression Profiling -- methods
- Gene Expression Regulation, Neoplastic
- Genetic Loci
- Head and Neck Neoplasms -- genetics
- Humans
- Introns -- genetics
- Models, Biological
- Nucleotide Motifs -- genetics
- Phosphorylation
- Polymerase Chain Reaction
- Protein Binding
- Protein Biosynthesis -- genetics
- Protein Isoforms -- genetics
- RNA Polymerase II -- metabolism
- RNA, Messenger -- genetics
- Regulatory Sequences, Nucleic Acid -- genetics
- Reproducibility of Results
- Tumor Hypoxia -- genetics
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Publication Type: Journal Article
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