Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly. [electronic resource]
Producer: 20170515ISSN:- 1098-5514
- Carrier Proteins -- metabolism
- Cell Line
- DNA-Binding Proteins -- metabolism
- Ethylenediamines -- pharmacology
- G2 Phase Cell Cycle Checkpoints
- HEK293 Cells
- HIV Infections -- virology
- HIV-1 -- metabolism
- Host-Pathogen Interactions
- Humans
- Monomeric GTP-Binding Proteins -- metabolism
- Myeloid Cells -- virology
- Protein Serine-Threonine Kinases
- Protein Structure, Tertiary
- SAM Domain and HD Domain-Containing Protein 1
- Simian Immunodeficiency Virus -- metabolism
- Transcription Factors -- metabolism
- Ubiquitin-Protein Ligases -- metabolism
- Viral Regulatory and Accessory Proteins -- genetics
- Virus Replication
- Zinc -- metabolism
- vpr Gene Products, Human Immunodeficiency Virus -- genetics
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Publication Type: Journal Article
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