Rv0774c, an iron stress inducible, extracellular esterase is involved in immune-suppression associated with altered cytokine and TLR2 expression. [electronic resource]
Producer: 20170308Description: 126-138 p. digitalISSN:- 1618-0607
- Bacterial Proteins -- chemistry
- Catalytic Domain
- Cell Line
- Cloning, Molecular
- Cytokines -- antagonists & inhibitors
- DNA Mutational Analysis
- Enzyme Stability
- Escherichia coli -- genetics
- Esterases -- chemistry
- Gene Expression
- Host-Pathogen Interactions
- Humans
- Immunosuppression Therapy
- Lipopolysaccharides -- metabolism
- Monocytes -- drug effects
- Mutagenesis, Site-Directed
- Mycobacterium tuberculosis -- enzymology
- Substrate Specificity
- Temperature
- Toll-Like Receptor 2 -- antagonists & inhibitors
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Publication Type: Journal Article
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