Recombinant 3-Hydroxy 3-Methyl Glutaryl-CoA Reductase from Candida glabrata (Rec-CgHMGR) Obtained by Heterologous Expression, as a Novel Therapeutic Target Model for Testing Synthetic Drugs. [electronic resource]
Producer: 20170908Description: 1478-1490 p. digitalISSN:- 1559-0291
- Amino Acid Sequence
- Biocatalysis
- Candida glabrata -- enzymology
- Drug Evaluation, Preclinical
- Enzyme Stability
- Escherichia coli -- genetics
- Humans
- Hydrogen-Ion Concentration
- Hydroxymethylglutaryl CoA Reductases -- chemistry
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- chemical synthesis
- Kinetics
- Maltose-Binding Proteins -- metabolism
- Models, Molecular
- Molecular Targeted Therapy
- Protein Domains
- Recombinant Proteins -- chemistry
- Simvastatin -- pharmacology
- Solubility
- Substrate Specificity
- Temperature
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Publication Type: Journal Article
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