Targeting CD133 improves chemotherapeutic efficacy of recurrent pediatric pilocytic astrocytoma following prolonged chemotherapy. [electronic resource]
Producer: 20180205Description: 21 p. digitalISSN:- 1476-4598
- AC133 Antigen -- antagonists & inhibitors
- ATP Binding Cassette Transporter, Subfamily B -- metabolism
- Adolescent
- Astrocytoma -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Chemotherapy, Adjuvant
- Child
- Child, Preschool
- Drug Resistance, Neoplasm
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Infant
- Male
- NF-kappa B -- genetics
- Neoadjuvant Therapy
- Neoplasm Recurrence, Local -- drug therapy
- Phosphatidylinositol 3-Kinases -- genetics
- Proto-Oncogene Proteins c-akt -- genetics
- Signal Transduction
- Up-Regulation
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Publication Type: Journal Article
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