Therapeutics Targeting Drivers of Thoracic Aortic Aneurysms and Acute Aortic Dissections: Insights from Predisposing Genes and Mouse Models. [electronic resource]
Producer: 20180101Description: 51-67 p. digitalISSN:- 1545-326X
- Aortic Dissection -- genetics
- Angiotensin II -- metabolism
- Animals
- Antihypertensive Agents -- therapeutic use
- Aortic Aneurysm, Thoracic -- genetics
- Disease Models, Animal
- Genetic Predisposition to Disease
- Humans
- Losartan -- therapeutic use
- Marfan Syndrome -- genetics
- Mechanoreceptors
- Mice
- Muscle, Smooth, Vascular -- physiopathology
- Signal Transduction
- Transforming Growth Factor beta -- metabolism
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Publication Type: Journal Article; Review
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