COX-2/mPGES-1/PGE2 cascade activation mediates uric acid-induced mesangial cell proliferation. [electronic resource]
Producer: 20180220Description: 10185-10198 p. digitalISSN:- 1949-2553
- Aged
- Animals
- Case-Control Studies
- Cell Line
- Cell Proliferation -- drug effects
- Cyclin A2 -- metabolism
- Cyclin D1 -- metabolism
- Cyclooxygenase 2 -- genetics
- Cyclooxygenase 2 Inhibitors -- pharmacology
- Dinoprostone -- metabolism
- Dose-Response Relationship, Drug
- Female
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Gout -- enzymology
- Humans
- Hyperuricemia -- enzymology
- Male
- Mesangial Cells -- drug effects
- Mice
- Middle Aged
- Prostaglandin-E Synthases -- genetics
- RNA Interference
- S Phase Cell Cycle Checkpoints -- drug effects
- Signal Transduction -- drug effects
- Time Factors
- Transfection
- Uric Acid -- pharmacology
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Publication Type: Journal Article
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