Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells. [electronic resource]
Producer: 20180222Description: 6319-6329 p. digitalISSN:- 1949-2553
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- BRCA1 Protein -- genetics
- Cell Cycle -- drug effects
- Checkpoint Kinase 1 -- genetics
- Cytarabine -- pharmacology
- DNA Damage
- Daunorubicin -- pharmacology
- Dose-Response Relationship, Drug
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Leukemic
- Histone Deacetylase 1 -- genetics
- Histone Deacetylase 2 -- genetics
- Histone Deacetylase Inhibitors -- pharmacology
- Humans
- Hydroxamic Acids -- pharmacology
- Indoles -- pharmacology
- Leukemia, Myeloid, Acute -- drug therapy
- Panobinostat
- RNA Interference
- Rad51 Recombinase -- genetics
- Signal Transduction -- drug effects
- THP-1 Cells
- Transfection
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Publication Type: Journal Article
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