Novel Hybrid Molecules on the Basis of Steroids and (5Z,9Z)-Tetradeca-5,9-dienoic Acid: Synthesis, Anti-Cancer Studies and Human Topoisomerase I Inhibitory Activity. [electronic resource]
Producer: 20170905Description: 1126-1135 p. digitalISSN:- 1875-5992
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- DNA Topoisomerases, Type I -- metabolism
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Fatty Acids, Unsaturated -- chemistry
- Humans
- Molecular Docking Simulation
- Molecular Structure
- Steroids -- chemistry
- Structure-Activity Relationship
- Topoisomerase I Inhibitors -- chemical synthesis
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Publication Type: Journal Article
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