Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity. [electronic resource]
Producer: 20180222Description: 79557-79571 p. digitalISSN:- 1949-2553
- Animals
- Antineoplastic Agents, Phytogenic -- chemistry
- Catechin -- analogs & derivatives
- Cell Line, Tumor
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation, Neoplastic
- HEK293 Cells
- Humans
- Intracellular Signaling Peptides and Proteins
- Lung Neoplasms -- genetics
- MAP Kinase Kinase Kinases -- metabolism
- Melanoma -- drug therapy
- Mice, Inbred BALB C
- Molecular Docking Simulation
- NF-KappaB Inhibitor alpha -- metabolism
- NF-kappa B -- metabolism
- Neoplasm Invasiveness
- Phosphorylation
- Protein Binding
- Protein Conformation
- Signal Transduction
- Skin Neoplasms -- drug therapy
- Structure-Activity Relationship
- TNF Receptor-Associated Factor 6 -- antagonists & inhibitors
- Transfection
- Tumor Burden -- drug effects
- Ubiquitin-Conjugating Enzymes -- metabolism
- Ubiquitin-Protein Ligases -- antagonists & inhibitors
- Ubiquitination
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Publication Type: Journal Article
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