Targeting ODC1 inhibits tumor growth through reduction of lipid metabolism in human hepatocellular carcinoma. [electronic resource]
Producer: 20170613Description: 1674-81 p. digitalISSN:- 1090-2104
- Animals
- Apoptosis -- genetics
- Blotting, Western
- Carcinoma, Hepatocellular -- enzymology
- Caspase 9 -- genetics
- Cell Cycle -- genetics
- Cell Line, Tumor
- Cell Proliferation -- genetics
- Cyclin E -- genetics
- Gene Expression Regulation, Neoplastic
- Gene Regulatory Networks
- Humans
- Kruppel-Like Transcription Factors -- genetics
- Lipid Metabolism -- genetics
- Liver Neoplasms -- enzymology
- Male
- Mice, Inbred BALB C
- Mice, Nude
- Oncogene Proteins -- genetics
- Ornithine Decarboxylase -- genetics
- PPAR gamma -- genetics
- Poly (ADP-Ribose) Polymerase-1 -- genetics
- RNA Interference
- RNAi Therapeutics -- methods
- Reverse Transcriptase Polymerase Chain Reaction
- Xenograft Model Antitumor Assays -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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