Histone deacetylase inhibition is cytotoxic to oligodendrocyte precursor cells in vitro and in vivo. [electronic resource]
Producer: 20170327Description: 53-61 p. digitalISSN:- 1873-474X
- 2',3'-Cyclic-Nucleotide Phosphodiesterases -- genetics
- Animals
- Animals, Newborn
- Caspases -- metabolism
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Cerebral Cortex -- cytology
- Dose-Response Relationship, Drug
- Embryo, Mammalian
- Gene Expression Regulation, Developmental -- drug effects
- Histone Deacetylase Inhibitors -- pharmacology
- Histone Deacetylases -- genetics
- Hydroxamic Acids -- pharmacology
- In Vitro Techniques
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Oligodendroglia -- drug effects
- Stem Cells -- drug effects
- Time Factors
- Vorinostat
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Publication Type: Journal Article
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