Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism. [electronic resource]
Producer: 20170814Description: 2250-60 p. digitalISSN:- 1550-6606
- Adaptor Proteins, Signal Transducing -- metabolism
- Animals
- Cell Proliferation
- Cell Survival
- Glycolysis -- drug effects
- Mechanistic Target of Rapamycin Complex 1
- Mice
- Multiprotein Complexes -- genetics
- Phosphorylation -- drug effects
- Precursor Cells, B-Lymphoid -- drug effects
- Regulatory-Associated Protein of mTOR
- Signal Transduction
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases -- deficiency
- Transcription Factors
- bcl-X Protein -- genetics
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Publication Type: Journal Article
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