Increased trabecular bone and improved biomechanics in an osteocalcin-null rat model created by CRISPR/Cas9 technology. [electronic resource]
Producer: 20171204Description: 1169-1179 p. digitalISSN:- 1754-8411
- Absorptiometry, Photon
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Biomechanical Phenomena
- Body Composition
- CRISPR-Cas Systems -- genetics
- Cancellous Bone -- diagnostic imaging
- Femur -- diagnostic imaging
- Founder Effect
- Genetic Techniques
- Glucose Tolerance Test
- INDEL Mutation -- genetics
- Insulin -- metabolism
- Male
- Models, Animal
- Osteocalcin -- chemistry
- Rats
- Species Specificity
- X-Ray Microtomography
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
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