MK-2206 sensitizes BRCA-deficient epithelial ovarian adenocarcinoma to cisplatin and olaparib. [electronic resource]
Producer: 20171002Description: 550 p. digitalISSN:- 1471-2407
- BRCA1 Protein -- genetics
- Carcinoma, Ovarian Epithelial
- Cell Line, Tumor
- Cell Survival -- drug effects
- Cisplatin -- pharmacology
- Drug Synergism
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Heterocyclic Compounds, 3-Ring -- pharmacology
- Humans
- Mutation
- Neoplasms, Glandular and Epithelial -- drug therapy
- Ovarian Neoplasms -- drug therapy
- Phosphorylation
- Phthalazines -- pharmacology
- Piperazines -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
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Publication Type: Journal Article
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