Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease. [electronic resource]
Producer: 20171002Description: 90-9 p. digitalISSN:- 1523-1755
- Anilides -- pharmacology
- Animals
- Cell Proliferation -- drug effects
- Chlorides -- blood
- Cyclic AMP -- blood
- Cystic Fibrosis Transmembrane Conductance Regulator -- metabolism
- Disease Models, Animal
- Dogs
- Down-Regulation
- Epithelial Cells -- metabolism
- Female
- Histone Deacetylase 6
- Histone Deacetylase Inhibitors -- pharmacology
- Histone Deacetylases -- genetics
- Humans
- Hydroxamic Acids -- pharmacology
- Kidney -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Polycystic Kidney, Autosomal Dominant -- genetics
- TRPP Cation Channels -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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