Sphingosylphosphorylcholine promotes the differentiation of resident Sca-1 positive cardiac stem cells to cardiomyocytes through lipid raft/JNK/STAT3 and β-catenin signaling pathways. [electronic resource]
Producer: 20160908Description: 1579-88 p. digitalISSN:- 0006-3002
- Animals
- Antigens, Ly -- metabolism
- Biomarkers -- metabolism
- Cell Differentiation -- drug effects
- Cells, Cultured
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- JNK Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Membrane Microdomains -- drug effects
- Membrane Proteins -- metabolism
- Mice, Inbred C57BL
- Myocytes, Cardiac -- drug effects
- Phosphorylcholine -- analogs & derivatives
- Protein Kinase Inhibitors -- pharmacology
- STAT3 Transcription Factor -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Sphingosine -- analogs & derivatives
- Stem Cells -- drug effects
- Time Factors
- beta Catenin -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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