Anti-melanogenic effects of Aster spathulifolius extract in UVB-exposed C57BL/6J mice and B16F10 melanoma cells through the regulation of MAPK/ERK and AKT/GSK3β signalling. [electronic resource]
Producer: 20170509Description: 503-13 p. digitalISSN:- 2042-7158
- Animals
- Aster Plant -- chemistry
- Cell Line, Tumor
- Chromatography, High Pressure Liquid
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Extracellular Signal-Regulated MAP Kinases -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta -- antagonists & inhibitors
- Hyperpigmentation -- enzymology
- Melanins -- metabolism
- Melanocytes -- drug effects
- Melanoma, Experimental -- drug therapy
- Mice, Inbred C57BL
- Microphthalmia-Associated Transcription Factor -- metabolism
- Monophenol Monooxygenase -- metabolism
- Phosphorylation
- Phytotherapy
- Plant Extracts -- isolation & purification
- Plants, Medicinal
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Skin -- drug effects
- Skin Lightening Preparations -- isolation & purification
- Skin Neoplasms -- drug therapy
- Skin Pigmentation -- drug effects
- Spectrometry, Mass, Electrospray Ionization
- Time Factors
- Ultraviolet Rays
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Publication Type: Journal Article
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