Prevention of methotrexate cytotoxicity by asparaginase inhibition of methotrexate polyglutamate formation. [electronic resource]
Producer: 19850125Description: 217-20 p. digitalISSN:- 0008-5472
- Animals
- Asparaginase -- pharmacology
- Asparagine -- analysis
- Biological Transport -- drug effects
- Cell Survival -- drug effects
- DNA Replication -- drug effects
- Glutamates -- analysis
- Glutamic Acid
- Glutamine -- analysis
- Kinetics
- Leukemia L5178 -- pathology
- Leukemia, Experimental -- pathology
- Methotrexate -- analogs & derivatives
- Mice
- Peptides -- metabolism
- Polyglutamic Acid -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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