PX-RICS-deficient mice mimic autism spectrum disorder in Jacobsen syndrome through impaired GABAA receptor trafficking. [electronic resource]
Producer: 20160802Description: 10861 p. digitalISSN:- 2041-1723
- Animals
- Autism Spectrum Disorder -- genetics
- Behavior, Animal -- drug effects
- Clonazepam -- pharmacology
- Excitatory Amino Acid Agonists -- toxicity
- GABA Modulators -- pharmacology
- GTPase-Activating Proteins -- genetics
- Grooming
- Jacobsen Distal 11q Deletion Syndrome -- genetics
- Kainic Acid -- toxicity
- Mice
- Mice, Knockout
- Olfactory Perception -- drug effects
- Protein Transport -- genetics
- Receptors, GABA-A -- metabolism
- Seizures -- chemically induced
- Social Behavior
- Stereotyped Behavior -- drug effects
- Vocalization, Animal -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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