Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment. [electronic resource]
Producer: 20161213Description: 329ra34 p. digitalISSN:- 1946-6242
- Amino Acids -- metabolism
- Animals
- CD36 Antigens -- metabolism
- Carcinoma, Ovarian Epithelial
- Cell Death -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cyclization
- Disease Models, Animal
- Female
- Humans
- Mice, Inbred C57BL
- Neoplasm Grading
- Neoplasms, Glandular and Epithelial -- drug therapy
- Ovarian Neoplasms -- drug therapy
- Peptides, Cyclic -- pharmacology
- Regression Analysis
- Saposins -- chemistry
- Thrombospondin 1 -- pharmacology
- Tissue Array Analysis
- Tumor Microenvironment -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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