Smad4 Deficiency in Smooth Muscle Cells Initiates the Formation of Aortic Aneurysm. [electronic resource]
Producer: 20160629Description: 388-99 p. digitalISSN:- 1524-4571
- Animals
- Aorta -- metabolism
- Aortic Aneurysm -- genetics
- Cathepsins -- metabolism
- Cell Line
- Chemokines -- metabolism
- Chemotaxis
- Elastin -- metabolism
- Female
- Genetic Predisposition to Disease
- Macrophages -- metabolism
- Male
- Matrix Metalloproteinase 12 -- metabolism
- Mice, Inbred C57BL
- Mice, Knockout
- Muscle, Smooth, Vascular -- metabolism
- Myocytes, Smooth Muscle -- metabolism
- Phenotype
- Protein Serine-Threonine Kinases -- deficiency
- Proteolysis
- RNA Interference
- Rats
- Receptor, Transforming Growth Factor-beta Type II
- Receptors, Transforming Growth Factor beta -- deficiency
- Smad4 Protein -- deficiency
- Time Factors
- Transfection
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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