Heterogeneous Mechanisms of Secondary Resistance and Clonal Selection in Sarcoma during Treatment with Nutlin. [electronic resource]
Producer: 20160614Description: e0137794 p. digitalISSN:- 1932-6203
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Autophagy -- drug effects
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Clone Cells -- drug effects
- Drug Resistance, Neoplasm -- genetics
- Gene Expression Profiling
- Humans
- Imidazoles -- pharmacology
- Mutation
- Ploidies
- Proto-Oncogene Proteins c-mdm2 -- metabolism
- Pyrrolidines -- pharmacology
- Sarcoma -- drug therapy
- Sequence Analysis, RNA
- Signal Transduction -- drug effects
- Tumor Suppressor Protein p53 -- genetics
- para-Aminobenzoates -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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