Inhibition of the Rho/Rho kinase pathway prevents lipopolysaccharide-induced hyperalgesia and the release of TNF-α and IL-1β in the mouse spinal cord. [electronic resource]
Producer: 20160808Description: 14553 p. digitalISSN:- 2045-2322
- ADP Ribose Transferases -- pharmacology
- Amides -- pharmacology
- Animals
- Botulinum Toxins -- pharmacology
- Gene Expression Regulation
- Hindlimb
- Hot Temperature
- Hyperalgesia -- chemically induced
- Injections, Spinal
- Interleukin-1beta -- antagonists & inhibitors
- Lipopolysaccharides
- Male
- Mice
- Mice, Inbred C57BL
- Nociception -- physiology
- Pain Measurement
- Proto-Oncogene Proteins c-fos -- genetics
- Pyridines -- pharmacology
- Signal Transduction
- Spinal Cord Dorsal Horn
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- rho GTP-Binding Proteins -- antagonists & inhibitors
- rho-Associated Kinases -- antagonists & inhibitors
- rhoA GTP-Binding Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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