RQN-18690A (18-deoxyherboxidiene) targets SF3b, a spliceosome component, and inhibits angiogenesis. [electronic resource]
Producer: 20160720Description: 121-3 p. digitalISSN:- 1881-1469
- Cells, Cultured
- Enzyme Inhibitors -- pharmacology
- Fatty Alcohols -- pharmacology
- Human Umbilical Vein Endothelial Cells -- drug effects
- Humans
- Models, Molecular
- Molecular Structure
- Neovascularization, Physiologic -- drug effects
- Phosphoproteins -- antagonists & inhibitors
- Pyrans -- pharmacology
- RNA Splicing Factors
- Ribonucleoprotein, U2 Small Nuclear -- antagonists & inhibitors
- Spliceosomes -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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