cAMP signalling of Bordetella adenylate cyclase toxin through the SHP-1 phosphatase activates the BimEL-Bax pro-apoptotic cascade in phagocytes. [electronic resource]
Producer: 20161108Description: 384-98 p. digitalISSN:- 1462-5822
- Adenylate Cyclase Toxin -- metabolism
- Apoptosis -- physiology
- Apoptosis Regulatory Proteins -- metabolism
- Bcl-2-Like Protein 11
- Bordetella pertussis -- metabolism
- Cyclic AMP -- metabolism
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- genetics
- Host-Pathogen Interactions -- physiology
- Humans
- Macrophages -- metabolism
- Membrane Proteins -- metabolism
- Mitochondria -- metabolism
- Phagocytes -- metabolism
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Signal Transduction
- bcl-2-Associated X Protein -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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