SUMOylation-disrupting WAS mutation converts WASp from a transcriptional activator to a repressor of NF-κB response genes in T cells. [electronic resource]
Producer: 20160106Description: 1670-82 p. digitalISSN:- 1528-0020
- Adaptive Immunity -- genetics
- Blotting, Western
- Cell Line
- Electrophoretic Mobility Shift Assay
- Flow Cytometry
- Gene Expression Regulation -- immunology
- Humans
- Immunoprecipitation
- Mass Spectrometry
- Mutagenesis, Site-Directed
- Mutation
- NF-kappa B -- genetics
- Polymerase Chain Reaction
- Signal Transduction -- genetics
- Sumoylation
- Th1 Cells -- immunology
- Transcriptional Activation -- physiology
- Transfection
- Wiskott-Aldrich Syndrome Protein -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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