Acquired Resistance of EGFR-Mutant Lung Cancer to a T790M-Specific EGFR Inhibitor: Emergence of a Third Mutation (C797S) in the EGFR Tyrosine Kinase Domain. [electronic resource]
Producer: 20160329Description: 982-4 p. digitalISSN:- 2374-2445
- Adenocarcinoma -- drug therapy
- Adenocarcinoma of Lung
- Aged
- Antineoplastic Agents -- therapeutic use
- Biomarkers, Tumor -- antagonists & inhibitors
- Clinical Trials, Phase I as Topic
- DNA Mutational Analysis
- Drug Resistance, Neoplasm -- genetics
- Drug Substitution
- ErbB Receptors -- antagonists & inhibitors
- Female
- Genetic Predisposition to Disease
- Humans
- Lung Neoplasms -- drug therapy
- Middle Aged
- Molecular Targeted Therapy
- Mutation
- Phenotype
- Protein Kinase Inhibitors -- therapeutic use
- Protein Structure, Tertiary
- Time Factors
- Treatment Outcome
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Publication Type: Case Reports; Letter; Research Support, N.I.H., Extramural
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