Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex. [electronic resource]
Producer: 20160405Description: 7307 p. digitalISSN:- 2041-1723
- Animals
- Bone Marrow Cells
- Cell Differentiation -- genetics
- Craniosynostoses -- genetics
- HEK293 Cells
- Hematopoietic Stem Cells -- cytology
- Histones -- metabolism
- Humans
- Intellectual Disability -- genetics
- Leukemia, Myeloid -- genetics
- Mast Cells -- cytology
- Mice
- Mice, Inbred C57BL
- Mutation
- Promoter Regions, Genetic
- Repressor Proteins -- genetics
- Tumor Suppressor Proteins -- metabolism
- Ubiquitin Thiolesterase -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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