Marine lipopeptide Iturin A inhibits Akt mediated GSK3β and FoxO3a signaling and triggers apoptosis in breast cancer. [electronic resource]
Producer: 20160324Description: 10316 p. digitalISSN:- 2045-2322
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Bacillus megaterium -- metabolism
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Female
- Forkhead Box Protein O3
- Forkhead Transcription Factors -- antagonists & inhibitors
- Gene Expression Regulation, Neoplastic
- Glycogen Synthase Kinase 3 -- antagonists & inhibitors
- Glycogen Synthase Kinase 3 beta
- Humans
- MCF-7 Cells
- Mice
- Mice, Inbred BALB C
- Peptides, Cyclic -- pharmacology
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Transplantation, Heterologous
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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