Protection against Mycobacterium tuberculosis infection offered by a new multistage subunit vaccine correlates with increased number of IFN-γ+ IL-2+ CD4+ and IFN-γ+ CD8+ T cells. [electronic resource]
Producer: 20160309Description: e0122560 p. digitalISSN:- 1932-6203
- Adjuvants, Immunologic -- pharmacology
- Adolescent
- Adult
- Aged
- Animals
- Antibodies, Bacterial -- immunology
- Antigens, Bacterial -- blood
- Bacterial Load -- immunology
- CD4-Positive T-Lymphocytes -- immunology
- CD8-Positive T-Lymphocytes -- immunology
- Female
- Humans
- Immunization
- Interferon-gamma -- metabolism
- Interleukin-2 -- metabolism
- Lung -- microbiology
- Male
- Mice
- Mice, Inbred C57BL
- Middle Aged
- Mycobacterium tuberculosis -- immunology
- Polyproteins -- immunology
- Th1 Cells -- immunology
- Tuberculosis -- prevention & control
- Tuberculosis Vaccines -- immunology
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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