GPR40/FFA1 and neutral sphingomyelinase are involved in palmitate-boosted inflammatory response of microvascular endothelial cells to LPS. [electronic resource]
Producer: 20160104Description: 163-73 p. digitalISSN:- 1879-1484
- Cells, Cultured
- Dose-Response Relationship, Drug
- Endothelial Cells -- drug effects
- Humans
- Hydrolysis
- Inflammation -- enzymology
- Inflammation Mediators -- metabolism
- Interleukin-6 -- genetics
- Lipopolysaccharides -- pharmacology
- Microvessels -- drug effects
- Mitogen-Activated Protein Kinases -- metabolism
- NF-kappa B -- genetics
- Palmitic Acid -- pharmacology
- RNA Interference
- Receptors, G-Protein-Coupled -- genetics
- Signal Transduction -- drug effects
- Sphingomyelin Phosphodiesterase -- genetics
- Sphingomyelins -- metabolism
- Time Factors
- Transfection
- Up-Regulation
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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